Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
58756 | Catalysis Today | 2006 | 9 Pages |
Abstract
Pig liver cells cultured in the membrane bioreactor exhibited viability and liver specific functions at higher levels than those of cells cultured in batch systems. The rate of rofecoxib elimination by cells increased with increasing rofecoxib concentration in the range 0-400Â nM. Hepatocytes exhibited highest rates of albumin production and urea synthesis at 300-400Â nM rofecoxib concentration.
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Catalysis
Authors
Loredana De Bartolo, Simona Salerno, Lidietta Giorno, Sabrina Morelli, Giuseppe Barbieri, Efrem Curcio, Maria Rende, Enrico Drioli,