Article ID Journal Published Year Pages File Type
5877451 Cor et Vasa 2014 8 Pages PDF
Abstract
Twelve months dual antiplatelet therapy (DAPT) based on a combination of acetylsalicylic acid and purine receptor P2Y12 inhibitor is a standard for all patients with acute coronary syndrome (unstable angina pectoris, NSTEMI and STEMI). Previous sub-analysis of CURE and ACUITY studies suggested that DAPT could bring benefit even for patients treated by surgical revascularization. Sub-analysis of PLATO trial conducted on 1261 patients, who underwent surgical revascularization within 12 months, demonstrated a reduction of cardiovascular and total mortality within a group of patients treated by ticagrelor and acetylsalicylic acid compared to patients treated by clopidogrel and acetylsalicylic acid.
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