Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5880676 | The Journal of Pain | 2014 | 22 Pages |
Abstract
Next-gen RNA-Seq, combined with molecular genetics, provides a comprehensive and quantitative measurement of transcripts in TRPV1 lineage neurons and a contrasting transcriptome from non-TRPV1 neurons and cells. The transcriptome highlights previously unrecognized protein families, identifies multiple molecular circuits for excitatory or inhibitory autocrine and paracrine signaling, and suggests new combinatorial approaches to pain control.
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Authors
Samridhi C. Goswami, Santosh K. Mishra, Dragan Maric, Krisztian Kaszas, Gian Luigi Gonnella, Samuel J. Clokie, Hal D. Kominsky, Jacklyn R. Gross, Jason M. Keller, Andrew J. Mannes, Mark A. Hoon, Michael J. Iadarola,