Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5880796 | The Journal of Pain | 2013 | 13 Pages |
Abstract
Short-term AT2 activation is a potent contributor to thermal hypersensitivity, whereas long-term effects (such as hyperinnervation) also contribute to mechanical hypersensitivity. Pharmacologic blockade of AT2 signaling represents a potential therapeutic strategy aimed at biologic mechanisms underlying chronic inflammatory pain.
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Authors
Anuradha Chakrabarty, Zhaohui Liao, Peter G. Smith,