Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5889421 | Bone | 2016 | 8 Pages |
Abstract
Body and visceral fat weights as well as serum leptin level were increased in donepezil-treated mice compared to control, suggesting that donepezil effects on SNS influenced metabolic activity. Donepezil-treated mice had better bone quality than controls due to a decrease in osteoclasts number. These results indicate that donepezil is able to affect whole body energy metabolism and favors bone mass in young female WT mice.
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Authors
Hazem Eimar, Sharifa Alebrahim, Garthiga Manickam, Ahmed Al-Subaie, Lina Abu-Nada, Monzur Murshed, Faleh Tamimi,