| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890040 | Bone | 2014 | 10 Pages |
Abstract
Despite these results, and the presumed beneficial effect of vitamin D supplementation in deficient patients, clinical studies that address the effects of vitamin D deficiency or supplementation on fracture healing are scarce and remain inconclusive. We conclude that vitamin D has a role in fracture healing, but the available data are too inconsistent to elucidate how and in what manner.
Keywords
TGF-βIGFTNAPCalcidiolPDGFFGF1,25(OH)2D325(OH)DTissue-nonspecific alkaline phosphataseBoneFracture healinginterleukinTransforming Growth Factor Betatumor necrosis factor-alphaFractureVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)platelet-derived growth factorfibroblast growth factorInsulin-like growth factorTNF-αVitamin Dbone morphogenetic proteinsCalcitriolVitamin D deficiency
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Authors
Erwin A. Gorter, Neveen A.T. Hamdy, Natasha M. Appelman-Dijkstra, Inger B. Schipper,