Article ID Journal Published Year Pages File Type
5890191 Bone 2014 10 Pages PDF
Abstract
This study presents novel data regarding bone material strength in children with osteogenesis imperfecta. Results confirm that these properties are anisotropic. Elevated vascular porosity was observed in most specimens, and this parameter was associated with reduced bone material strength. These results offer insight toward understanding bone fragility and the role of intracortical porosity on the strength of bone tissue in children with osteogenesis imperfecta.
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Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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