Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5890622 | Bone | 2013 | 10 Pages |
Abstract
⺠Osteoporosis and osteoarthritis are major health problems in the elderly population, particularly in postmenopausal women, but their relationship remains unclear. ⺠Early ALN treatment completely prevented both subchondral bone loss and cartilage surface erosion caused by OVX. ⺠Late ALN treatment inhibited subchondral bone loss and significantly reduced cartilage erosion, although they did not recover to normal levels. ⺠Treatment for OP with bone resorption inhibitors reduces cartilage degeneration when menopause-related OP and OA coexist in same individuals.
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Authors
Songsong Zhu, Kan Chen, Yu Lan, Nan Zhang, Rulang Jiang, Jing Hu,