| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890625 | Bone | 2013 | 41 Pages |
Abstract
⺠COX2 gene therapy accelerates healing of multiple tibial fractures in the mouse. ⺠COX2 gene therapy increases recruitment and/or expansion of certain mesenchymal stem cell subpopulations in fracture calluses. ⺠COX2 gene therapy decreases cartilaginous callus formation during fracture healing. ⺠COX2 gene therapy increases angiogenesis-dependent cartilage remodeling. ⺠These effects of COX2 gene therapy are associated with an earlier onset of bony bridging of the fracture gap.
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Authors
K.-H. William Lau, Vishal Kothari, Amitava Das, Xiao-Bing Zhang, David J. Baylink,