| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890629 | Bone | 2013 | 10 Pages |
Abstract
⺠Alkaline phosphatase (ALP) was investigated in tissues and serum from wild-type and different ALP knockout mice. ⺠All mouse tissues, except liver and colon, contained significant ALP activity. ⺠Mouse serum consists mostly of bone ALP (four bone ALP isoforms) and both intestinal ALP isozymes dIALP and gIALP. ⺠These results should pave the way for the development of assays measuring bone-specific ALP in mouse serum. ⺠Since mouse hepatocytes do not express TNALP, we suggest renaming of the mouse gene to Alpb (“b” denotes bone).
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Authors
Cecilia Halling Linder, Ulrika H. Englund, Sonoko Narisawa, José Luis Millán, Per Magnusson,