| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890750 | Bone | 2012 | 9 Pages |
Abstract
⺠Only mature osteoclasts are sources of anabolic stimuli for osteoblasts. ⺠Osteopetrotic osteoclasts secrete anabolic factors for osteoblasts. ⺠Enhanced osteoclast survival compensates for the lack of resorption derived factors. ⺠Osteoclasts on non-natural substrates fail to secrete anabolic molecules. ⺠Interaction with matrix strongly modulates anabolic potential of the osteoclasts.
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Authors
Kim Henriksen, Kim V. Andreassen, Christian S. Thudium, Karoline N.S. Gudmann, Ilana Moscatelli, Catherine E. Crüger-Hansen, Ansgar S. Schulz, Morten H. Dziegiel, Johan Richter, Morten A. Karsdal, Anita V. Neutzsky-Wulff,