| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890765 | Bone | 2012 | 11 Pages |
Abstract
⺠IFT80 was highly expressed in bone tissue and during osteoblast differentiation. ⺠Silencing IFT80 led to either shortening or loss of cilia and blocked osteogenesis. ⺠Overexpression of Gli2 rescued osteogenic deficiency of IFT80-silenced cells. ⺠Introduction of SAG promoted osteogenesis, which was inhibited by silencing IFT80. ⺠IFT80 stimulates osteogenesis through regulating Hedgehog/Gli signal pathway.
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Authors
Shuying Yang, Changdong Wang,