| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890780 | Bone | 2012 | 8 Pages |
Abstract
⺠Intracellular calcium signaling of osteocytes is dependent on the profiles of mechanical stimulation. ⺠Osteocytic networks are more responsive to steady fluid flow than to oscillatory fluid flow. ⺠Responsive percentages of osteocytes have no significant difference under steady and oscillatory flows. ⺠Spatiotemporal characters of the calcium signaling transients in osteocytes vary significantly under different flow profiles. ⺠Endoplasmic reticulum calcium store, extracellular calcium source, and ATP pathways are critical for calcium signaling of osteocytes.
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Authors
X. Lucas Lu, Bo Huo, Miri Park, X. Edward Guo,