Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5890791 | Bone | 2012 | 9 Pages |
Abstract
⺠We investigated, for the first time, the associations of estrogen with adiponectin in osteoblastic OPG and RANKL expression. ⺠We revealed that E2 blocked the activation of adiponectin-induced p38 MAPK. ⺠We revealed that E2 suppressed the adiponectin-regulated OPG and RANKL expression. ⺠E2 attenuated both the decrease of OPG and increase of RANKL expression regulated by adiponectin with time.
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Authors
Qing-Ping Wang, Li Yang, Xian-Ping Li, Hui Xie, Er-Yuan Liao, Min Wang, Xiang-Hang Luo,