| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5890877 | Bone | 2013 | 10 Pages |
Abstract
Fourteen human bone samples (10 femoral necks and 4 femoral heads) from individuals with osteoporotic femoral neck fractures as well as from healthy individuals were analyzed. Fluorescence intensity maps were matched with BE images and correlated with calcium (Ca) content. We found that Zn and Pb had significantly increased levels in the cement lines of all samples compared to the surrounding mineralized bone matrix. Pb and Sr levels were found to be correlated with the degree of mineralization. Interestingly, Zn intensities had no correlation with Ca levels. We have shown for the first time that there is a differential accumulation of the trace elements Zn, Pb and Sr in BSUs of human bone indicating different mechanisms of accumulation.
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Authors
B. Pemmer, A. Roschger, A. Wastl, J.G. Hofstaetter, P. Wobrauschek, R. Simon, H.W. Thaler, P. Roschger, K. Klaushofer, C. Streli,