Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5890946 | Bone | 2013 | 5 Pages |
Abstract
In vitamin D-deficient hip fracture patients, oral supplementation with cholecalciferol and ergocalciferol had no effect on total serum 1,25(OH)2D, and comparable effects on DBP and free vitamin D metabolite concentrations. This is despite cholecalciferol having greater effects than ergocalciferol in increasing total 25OHD, and in increasing ionized calcium in treatment-adherent subjects. These findings may explain why cholecalciferol and ergocalciferol supplementation result in similar magnitudes of PTH reduction, but implicate potential differences in other vitamin D metabolites, such as 24,25(OH)2D, that could explain their different effects on ionized calcium.
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Authors
Paul Glendenning, Gerard T. Chew, Charles A. Inderjeeth, Mario Taranto, William D. Fraser,