Article ID Journal Published Year Pages File Type
5891075 Bone 2013 10 Pages PDF
Abstract
► ALCAM/CD166 expression in CD45 −CD31 −Ter119 −Sca1 − osteoblasts increases during the first week of culture and then dramatically declines with culture duration. ► ALCAM/CD166 expression in osteoblasts directly correlates with hematopoietic activity and function of LSK cells co-cultured with osteoblasts. ► LSK cells co-cultured with Lin −OPN + CD166 + CD44 + CD90 + osteoblasts sustain the highest in vivo repopulating potential in primary and secondary recipients.
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