| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891175 | Bone | 2013 | 9 Pages |
Abstract
⺠Estrogen Therapy and Hormone Therapy effectively prevent and treat osteoporosis but have significant side effect profiles. ⺠SERMs (Selective Estrogen Receptor Modulators) exhibit a more favorable side effect profile ⺠However currently available SERMs are substantially less effective in bone than classical estrogens ⺠Discussion of ER pharmacology and ligands including endogenous SERMs ⺠Translation of ER pharmacology into new medicines (such as TSECs) for the treatment and prevention of osteoporosis.
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Authors
Erik R. Nelson, Suzanne E. Wardell, Donald P. McDonnell,