Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891178 | Bone | 2013 | 10 Pages |
Abstract
⺠We devised a method to extract RNA from trabecular bone osteocytes. ⺠C5 caudal vertebra was subjected to single and repetitive dose of compression loading. ⺠Trabecular osteocytic RNA was analyzed for changes in global gene expression. ⺠We found multiple load-regulated genes. ⺠Asporin and Wnt5a are genes that may regulate the load-induced bone anabolic effect.
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Authors
Elad Wasserman, Duncan Webster, Gisela Kuhn, Malka Attar-Namdar, Ralph Müller, Itai Bab,