Article ID Journal Published Year Pages File Type
5891178 Bone 2013 10 Pages PDF
Abstract
► We devised a method to extract RNA from trabecular bone osteocytes. ► C5 caudal vertebra was subjected to single and repetitive dose of compression loading. ► Trabecular osteocytic RNA was analyzed for changes in global gene expression. ► We found multiple load-regulated genes. ► Asporin and Wnt5a are genes that may regulate the load-induced bone anabolic effect.
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Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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