Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891217 | Bone | 2013 | 10 Pages |
Abstract
⺠We have investigated how the Atlantic salmon vertebra responds to exercise induced mechanical load. ⺠Exercise activate osteoblasts and osteocytes and increases expression of genes involved in osteoid production. ⺠Substance P was identified as a key component in bone cell activation upon mechanical load. ⺠We suggest that an alternative autocrine pathway is involved in mechano-sensing and bone modeling in bone lacking the canalaculi system.
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Authors
Elisabeth Ytteborg, Jacob Seilø Torgersen, Mona Elisabeth Pedersen, Ståle J. Helland, Barbara Grisdale-Helland, Harald Takle,