Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891270 | Bone | 2012 | 9 Pages |
Abstract
⺠A prospective cohort study to identify a predictor of cardiovascular events (CVD). ⺠We enrolled 738 predialysis outpatients with chronic kidney disease (CKD). ⺠Serum bone markers, 25-hydroxyvitamin D, phosphaturic hormones were measured. ⺠Only intact fibroblast growth factor-23 (FGF23) predicted CVD before dialysis onset. ⺠FGF23 levels did not predict CVD if we continued follow-up after dialysis onset.
Keywords
ACE-IKDIGOpTHFGF23ARBBSAPIQRNRIALB1,25DEGFRCKD-MBD1,25-dihydroxyvitamin D25-hydroxyvitamin D95% CIAlbuminALPbone-specific alkaline phosphataseAlkaline phosphataseAngiotensin converting enzyme inhibitorstandard deviationNet reclassification improvementPeripheral arterial diseasecoronary artery diseasecardiovascular diseasechronic kidney diseasekidney disease: improving global outcomesDiabetes mellitusCVDBMIRisk stratificationCAD95% confidence intervalfibroblast growth factor 23Pulse pressureBlood pressuremineral metabolismMultiple imputationinterquartile rangeAngiotensin receptor blockerestimated glomerular filtration rateheart failurehazard ratioparathyroid hormonePADCalcium
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
Chikako Nakano, Takayuki Hamano, Naohiko Fujii, Yoshitsugu Obi, Isao Matsui, Kodo Tomida, Satoshi Mikami, Kazunori Inoue, Akihiro Shimomura, Yasuyuki Nagasawa, Noriyuki Okada, Yoshiharu Tsubakihara, Hiromi Rakugi, Yoshitaka Isaka,