| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891326 | Bone | 2013 | 10 Pages |
Abstract
⺠Cx43 is the most abundant gap junction protein expressed in bone cells. ⺠Cx43 forms gap junctions, hemichannels and serves as a scaffold that regulates intracellular signaling in bone cells. ⺠Through these diverse mechanisms, Cx43 regulates the response of bone to pharmacologic, hormonal and mechanical stimuli. ⺠Understanding the role of Cx43 in bone cell function provides new opportunities to treat bone diseases.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
Lilian I. Plotkin, Teresita Bellido,