Article ID Journal Published Year Pages File Type
5891354 Bone 2013 8 Pages PDF
Abstract
► The effects of combination treatments with eldecalcitol and alendronate or alfacalcidol and alendronate are examined in ovariectomized rats. ► Eldecalcitol with alendronate therapy inhibits bone resorption, while maintaining bone formation by histomorphometric analysis. ► Alfacalcidol with alendronate therapy inhibits the histological parameters of both bone resorption and formation. ► This study suggests eldecalcitol with alendronate therapy has therapeutic advantages over alfacalcidol with alendronate therapy.
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