Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891354 | Bone | 2013 | 8 Pages |
Abstract
⺠The effects of combination treatments with eldecalcitol and alendronate or alfacalcidol and alendronate are examined in ovariectomized rats. ⺠Eldecalcitol with alendronate therapy inhibits bone resorption, while maintaining bone formation by histomorphometric analysis. ⺠Alfacalcidol with alendronate therapy inhibits the histological parameters of both bone resorption and formation. ⺠This study suggests eldecalcitol with alendronate therapy has therapeutic advantages over alfacalcidol with alendronate therapy.
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Authors
Masanori Sugimoto, Nobuko Futaki, Masahiro Harada, Shinsuke Kaku,