Article ID Journal Published Year Pages File Type
5891378 Bone 2013 9 Pages PDF
Abstract
► This study investigated the role of CCR1 and CCL3 in bone remodeling induced by mechanical loading in mice. ► Bone remodeling was significantly decreased in CCL3−/− and CCR1−/− mice and in animals treated with Met-RANTES. ► CCR1 is pivotal for bone remodeling induced by mechanical loading and these actions depend, at least in part, on CCL3.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
Authors
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