| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891428 | Bone | 2013 | 7 Pages |
Abstract
⺠Quantitative computed tomography image processing techniques were used to assess foot bone strength noninvasively in acute Charcot neuroarthropathy. ⺠BMD was lower in Charcot patients versus diabetic, neuropathic controls, but indices of compressive and bending strength were maintained. ⺠Geometric results may reflect an inflammation-mediated response to bone injury rather than true maintenance of bone strength. ⺠Clinical quantitative computed tomography precludes clear discernment between functional bone adaptation and injury response, such as woven bone apposition. ⺠Improved spatial resolution will clarify the effects of Charcot neuroarthopathy on lower extremity bone strength and fracture risk.
Keywords
Ct.ThTt.ArμCTBMDMet2DXAQUSsecond metatarsalHR-pQCTCt.ArBone mineral densityMicro-computed tomographyHigh-resolution peripheral quantitative computed tomographycomputed tomographydual-energy X-ray absorptiometryDiabetes mellitusQuantitative ultrasoundBuckling ratioCharcot neuroarthropathyHydroxyapatitehounsfield unitperipheral neuropathyFifth metatarsaltotal cross-sectional area
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Authors
David J. Gutekunst, Kirk E. Smith, Paul K. Commean, Kathryn L. Bohnert, Fred W. Prior, David R. Sinacore,