Article ID Journal Published Year Pages File Type
5891435 Bone 2013 10 Pages PDF
Abstract
► In vivo evaluation revealed that superimposing nanoscale features on endosseous titanium surfaces alters the early molecular events involved in osseointegration. ► This in vivo model allows for detailed gene profiling that reveals possible early events impacting the implant/bone interface. ► Both immune regulatory gene profiles (downregulation) and skeletal/ossification gene profiles (upregulation) changed in a nanoscale-dependent manner.
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Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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