| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891446 | Bone | 2013 | 11 Pages |
Abstract
⺠Calvarial MSC isolated from synostoses displayed a constitutive osteogenic activity. ⺠They expressed higher levels of LMP and target genes compared to normal suture cells. ⺠The overactive osteogenic phenotype was corrected when LMP expression was silenced. ⺠LMP silencing induced down-regulation of osteo-specific transcription factors.
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Authors
Wanda Lattanzi, Marta Barba, Federica Novegno, Luca Massimi, Valentina Tesori, Gianpiero Tamburrini, Salvatore Galgano, Camilla Bernardini, Massimo Caldarelli, Fabrizio Michetti, Concezio Di Rocco,