Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891525 | Bone | 2011 | 10 Pages |
Abstract
⺠Sclerostin expression enhanced by BMPs and coupled to osteoblast mineralization. ⺠BMPs, Wnt3a and PTH do not directly activate sclerostin promoter. ⺠BMP2 increases expression of several sclerostin inhibitors. ⺠MEF2B increased activity of the promoter and ECR5 element. ⺠No ECR5 enhancer activity in human osteosarcoma cells.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
Longchuan Yu, Marissa van der Valk, Jin Cao, Chun-Ya E. Han, Todd Juan, Michael B. Bass, Chetan Deshpande, Michael A. Damore, Richard Stanton, Philip Babij,