Article ID Journal Published Year Pages File Type
5891752 Bone 2011 9 Pages PDF
Abstract
► Methylation of a CpG island was inversely associated with ALPL expression and activity in several cell types ► Methylation was low in human osteoblasts, intermediate in lining cells and high in osteocytes ► DNA demethylation by AzadC induced ALPL expression ► DNA methylation regulates ALPL through cell transitions in the osteoblastic lineage
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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