| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891798 | Bone | 2011 | 12 Pages |
Abstract
⺠Gene expression profiling reveals prognostic subgroups in canine osteosarcoma. ⺠This molecular signature is highly preserved in human osteosarcoma patients. ⺠It recapitulates a soft tissue sarcoma profile with potential bone-specific factors. ⺠The narrower genetic diversity of dogs simplifies pathological stratification. ⺠This unmasks biologically and clinically relevant molecular osteosarcoma subtypes.
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Authors
Milcah C. Scott, Aaron L. Sarver, Katherine J. Gavin, Venugopal Thayanithy, David M. Getzy, Robert A. Newman, Gary R. Cutter, Kerstin Lindblad-Toh, William C. Kisseberth, Lawrence E. Hunter, Subbaya Subramanian, Matthew Breen, Jaime F. Modiano,