Article ID Journal Published Year Pages File Type
5891849 Bone 2011 9 Pages PDF
Abstract
► Strontium ranelate induces in human osteoarthritic subchondral bone osteoblasts a decreased resorptive activity. ► Strontium ranelate modulates in human osteoarthritic subchondral bone osteoblasts the synthesis of key factors leading to bone resorption. ► Strontium ranelate could limit the extent of human osteoarthritic subchondral bone matrix degradation through the inhibition of MMPs.
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