Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5891874 | Bone | 2012 | 9 Pages |
Abstract
⺠N-cadherin mediated adherens junctions are formed between cells in the perichondrium during osteogenesis. ⺠N-cadherin mediated adherens junctions activate PI3K signaling cascade in osteoblasts leading to increased osteogenesis. ⺠Knockout of β-catenin and Pten, adherens junction proteins conditionally in preosteoblasts using Dermo1cre affects N-cadherin adherens junction formation.
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Authors
Anyonya R. Guntur, Clifford J. Rosen, Michael C. Naski,