Article ID Journal Published Year Pages File Type
5891878 Bone 2012 6 Pages PDF
Abstract
► A hydrostatic compression system was used to examine Ihh signal transduction under the influence of mechanical load. ► Hydrostatic compression increased both Ihh gene expression and Ihh-responsive Gli-luciferase activity. ► These increases were aborted by disrupting the primary cilia structure with chloral hydrate.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
Preview
Primary cilia modulate Ihh signal transduction in response to hydrostatic loading of growth plate chondrocytes
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