| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5891935 | Bone | 2012 | 13 Pages |
Abstract
⺠High-glucose alters biomineralization process in osteoblastic cells. ⺠High-glucose raises the amount, but diminishes the quality of mineral deposited. ⺠High glucose increases RANKL, osteocalcin, BSP and Cbfa and decreases OPG expression. ⺠High-glucose increases the expression of IL1beta, IL6, IL8, MCP-1 and IL10 mRNAs. ⺠Expression of TLR-2, -3 and -4 in osteoblastic cells seems susceptible to osmotic stress.
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Authors
A. GarcÃa-Hernández, H. Arzate, I. Gil-ChavarrÃa, R. Rojo, L. Moreno-Fierros,