Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5892063 | Bone | 2011 | 6 Pages |
Abstract
⺠Study investigated if statins prevent acute-phase response to aminobisphosphonates. ⺠Zoledronic acid increased pro-inflammatory cytokine levels in post-menopausal women. ⺠Zoledronic acid induced flu-like symptoms in >50% study participants. ⺠Fluvastatin did not prevent symptoms or cytokine release induced by zoledronic acid. ⺠Fluvastatin does not prevent the acute-phase response to zoledronic acid.
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Authors
Keith Thompson, Fran Keech, David J. McLernon, Kumar Vinod, Robin J. May, William G. Simpson, Michael J. Rogers, David M. Reid,