Article ID Journal Published Year Pages File Type
5892106 Bone 2011 7 Pages PDF
Abstract
► Primary osteoblasts constitutively express death domain containing TRAIL receptors. ► Cell surface DR4 and DR5 expression is restricted to infected osteoblasts. ► Production of OPG by osteoblasts is inhibited following bacterial infection. ►Acute bacterial exposure sensitizes osteoblasts to the apoptotic actions of TRAIL.
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Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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