Article ID Journal Published Year Pages File Type
5892113 Bone 2011 9 Pages PDF
Abstract
► Demonstration of calcium role in regulating the effects of phosphate on osteoblasts. ► Calcium effect on ERK1/2 phosphorylation is not mediated by CaSR. ► Calcium effects involve the formation of calcium phosphate precipitates (CaPp). ► CaPp are not endocytosed, although lipid rafts are necessary to their effects.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
Preview
Phosphate-dependent stimulation of MGP and OPN expression in osteoblasts via the ERK1/2 pathway is modulated by calcium
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