Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5892371 | Bone | 2010 | 7 Pages |
Abstract
This study demonstrates a mobilization of EPC population during distraction osteogenesis in human limb-lengthening patients. Distraction strain provoked increases in the plasma levels of EPC-mobilizing cytokines, such as, VEGF and SDF-1. These findings suggest a possibility that therapeutical approaches which modulate EPC mobilization may speed bone healing by angiogenesis-osteogenesis coupling during distraction osteogenesis.
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Authors
Dong Yeon Lee, Tae-Joon Cho, Hye Ran Lee, Moon Seok Park, Won Joon Yoo, Chin Youb Chung, In Ho Choi,