Quantitative computed tomography (QCT) of the forearm using general purpose spiral whole-body CT scanners: Accuracy, precision and comparison with dual-energy X-ray absorptiometry (DXA)

Whole-body spiral CT scanners allow densitometric evaluations of the distal radius with good accuracy and very good precision. This original and convenient method provides a tool to further investigate cortical and trabecular bone variables in the peripheral skeleton in osteoporotic patients. These assessments, coupled with evaluation of the effects on cortical and trabecular bone measured in response to therapies for osteoporosis, may advance our understanding of the contributors to non-vertebral fracture occurrence.