| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5894603 | Placenta | 2015 | 13 Pages |
Abstract
Maternal diabetic environment seems to alter umbilical cord expression of genes involved in the regulation of vascular development and function with simultaneous umbilical vessel muscle layer thickening. These alterations suggest vascular phenotypic modifications, which in turn may lead to long-term vascular consequences in various tissues in infants of diabetic mothers.
Keywords
Dll1Myocyte enhancer factor 2CNotch4endothelin receptor type BRT-PCREDNRBBMP4EDN1NppbMMP2αSMAMEF2CMPOLeukocyte common antigenAlpha-smooth muscle actinendothelin 1PregnancyGene expressionfold changedelta-like 1Type 1 diabetesDAVIDMicroarraymatrix metalloproteinase 2myeloperoxidaseNewbornGene ontologyreal-time polymerase chain reactionbone morphogenetic protein 4
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Authors
A. Koskinen, L. Lehtoranta, A. Laiho, J. Laine, P. Kääpä, H. Soukka,