| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5894771 | Placenta | 2015 | 8 Pages |
Abstract
Prenatal ethanol exposure compromises fetal growth and placentation in a dose-responsive manner. Ethanol's adverse effects on placental development are mediated by: 1) altered branching morphogenesis in labyrinthine zone; 2) suppression of invasive trophoblastic precursor cells; and 3) inhibition of trophoblastic cell adhesion and motility, corresponding with reduced ASPH and Notch-1 protein expression.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Developmental Biology
Authors
F. Gundogan, J. Gilligan, W. Qi, E. Chen, R. Naram, S.M. de la Monte,