Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5895091 | Placenta | 2015 | 11 Pages |
Abstract
Nrf2 has an anti-inflammatory effect in human fetal membranes. It is decreased with term labour and preterm chorioamnionitis; and Nrf2 silencing increases inflammation- and infection-induced pro-inflammatory cytokines. Further studies are required to determine if agents that can increase Nrf2 expression may be a potential therapeutic strategy in the treatment and management of infection-induced preterm labour.
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Authors
R. Lim, G. Barker, M. Lappas,