Article ID Journal Published Year Pages File Type
58951 Chinese Journal of Catalysis 2015 6 Pages PDF
Abstract

The one-pot eight-component reaction between Meldrum's acid, an aromatic aldehyde, and an aryl amine was achieved in the presence of citric acid catalyst. The corresponding dispirohydroquinolines were obtained in good yields with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.

Graphical AbstractThe one-pot eight-component reaction between Meldrum's acid, an aromatic aldehyde and an arylamine was achieved in the presence of citric acid as the catalyst. The corresponding dispirohydroquinoline was obtained in good yield with excellent diastereoselectivity. This method is a combination of the Knoevenagel and Michael reactions.Figure optionsDownload full-size imageDownload as PowerPoint slide

Related Topics
Physical Sciences and Engineering Chemical Engineering Catalysis
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