Article ID Journal Published Year Pages File Type
5895146 Placenta 2014 7 Pages PDF
Abstract
Cortisol increases aromatase expression via induction of CRH and hCG production and subsequent elevation of cAMP level and enrichment of Sp1 at the aromatase promoter in human placental syncytiotrophoblasts. These findings may account for the parallel increases of cortisol and estrogen production prior to the onset of parturition.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Developmental Biology
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