Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5895757 | Placenta | 2012 | 6 Pages |
Abstract
Increasing uterine artery Doppler PI reflects impaired placentation and increasing risk of preeclampsia. We show a positive association between uterine artery Doppler PI and both global arterial and aortic stiffness. We also show that increased maternal arterial stiffness is associated with a lower birth weight. These findings may represent evidence of an early effect of impaired placentation on the maternal vasculature. Alternatively, given the association between preeclampsia and later cardiovascular disease, ineffective placentation may result from impaired arterial function.
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Authors
T.R. Everett, A.A. Mahendru, C.M. McEniery, I.B. Wilkinson, C.C. Lees,