| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 5895781 | Placenta | 2013 | 9 Pages |
Abstract
Besides its role in gastric physiology our results clearly indicate regulatory functions of GKN1 in the EVT at the feto-maternal interface during pregnancy. Based on our findings in the JEG-3 choriocarcinoma cell line, an auto-/paracrine role of GKN1 for EVT motility and villous anchorage at the basal plate is conceivable. Thus, the tumor suppressor GKN1 is expressed in placental EVT and might contribute to the regulation of EVT migration/invasion.
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Authors
F.B. Fahlbusch, M. Ruebner, H. Huebner, G. Volkert, C. Zuern, F. Thiel, M. Koch, C. Menendez-Castro, D.L. Wachter, A. Hartner, W. Rascher,