Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5896235 | Placenta | 2009 | 7 Pages |
Abstract
This study demonstrates that with increasing maternal body mass index there is an increase in placental nitrative stress. There does not appear to be a corresponding increase in oxidative stress and indeed we demonstrate some evidence of a decrease in oxidative effects in these placenta samples. Potentially the formation of peroxynitrite may be consuming reactive oxygen species and reducing oxidative stress. There may be a shift in the balance between nitrative and oxidative stress, which may be a protective mechanism for the placenta.
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Authors
V.H.J. Roberts, J. Smith, S.A. McLea, A.B. Heizer, J.L. Richardson, L. Myatt,