Article ID Journal Published Year Pages File Type
5896478 Best Practice & Research Clinical Endocrinology & Metabolism 2015 15 Pages PDF
Abstract
Nuclear receptors belong to a superfamily of proteins that play central roles in human biology, orchestrating a large variety of biological functions in both health and disease. Understanding the interactions and regulatory pathways of NRs will allow development of potential therapeutic interventions for a multitude of disease processes. Non-coding RNAs have recently been discovered to have significant interactions with NR signalling pathways via a variety of biological connections. This review summarises the known interactions between ncRNAs and the NR superfamily in health, embryogenesis and a plethora of human diseases.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Endocrinology
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