Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897157 | Cytokine | 2013 | 9 Pages |
Abstract
⺠Secretion of factors in tumor cells varied considerably in magnitude and kinetics. ⺠Secretion of TGF-α, Flt-3L, PDGF-BB was cell line-specific. ⺠Correlation between factor level in conditioned medium and survival of tumor cells. ⺠Lower cytokine increase in tumor cells medium after fractionated than acute dose. ⺠Highest cytokine secretion in irradiated A549 cells and decreased bystander survival.
Keywords
TGF-βIL-10IFN-γIL-2FGF-2granulocyte monocyte colony stimulating factorIL-17GCSFIL-1αIL-8IL-1RAIP-10Tgf-αplatelet derived growth factor-BBIL-3sCD40LMIP-1FLT3-LGMCSFPDGF-AAIL-6PDGF-BBIL-15IL-1βMCP-1EGFinterleukin-1 receptor antagonistinterferon-γInterleukin-8Interleukin-10Interleukin-15interleukin-17interleukin-6Interleukin-1αInterleukin-1βInterleukin-3Interleukin-2Bystander effecttransforming growth factor-αtransforming growth factor-βtumor necrosis factor-αHuman tumor cell linesCytokinesConditioned mediumGranulocyte colony stimulating factorepidermal growth factorVascular endothelial growth factorVascular Endothelial Growth Factor (VEGF)TNF-αfibroblast growth factor-2soluble CD40 ligandmacrophage inflammatory protein-1Monocyte chemotactic protein-1
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Authors
Sejal Desai, Amit Kumar, S. Laskar, B.N. Pandey,