Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
5897183 | Cytokine | 2013 | 6 Pages |
Abstract
⺠Murine neutrophils contain activin A, which they spontaneously secrete in culture. ⺠Secretion is stimulated by TNF-α, whereas insulin blocks the response to TNF-α. ⺠LPS stimulates activin A release by bone marrow cells, but not isolated neutrophils. ⺠LPS stimulates activin A levels in the serum of TNF-α null mice. ⺠Neutrophils are a major source of activin A during inflammation in mice.
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Authors
Hui Wu, Yi Chen, Wendy R. Winnall, David J. Phillips, Mark P. Hedger,