Article ID Journal Published Year Pages File Type
5897183 Cytokine 2013 6 Pages PDF
Abstract
► Murine neutrophils contain activin A, which they spontaneously secrete in culture. ► Secretion is stimulated by TNF-α, whereas insulin blocks the response to TNF-α. ► LPS stimulates activin A release by bone marrow cells, but not isolated neutrophils. ► LPS stimulates activin A levels in the serum of TNF-α null mice. ► Neutrophils are a major source of activin A during inflammation in mice.
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